HIV-eradication related pending patents:
1. MOBILIZING HIV-INFECTED CELLS FROM LYMPHATIC RESERVOIRS
Application Number: PCT/US2017/019897
Filed: February 28, 2017​
Publication number: 20190010217
Abstract: Provided herein are methods of treating HIV infection, including retention of HIV+ T cells in viral reservoirs such as lymph nodes. More particularly, provided herein are methods in which an effective amount of a HIV Nef pathway inhibitor (e.g., anti-Nef agent) is administered to a subject in need thereof, whereby administration of the inhibitor treats HIV infection in the subject, decreases retention of HIV+ T cells in lymph nodes, and increases migration of HIV+ T cells from lymph nodes.
Type: Application
Inventors: Matthias Alexander Clauss, Bernhard Fidelis Maier
2. COMPOSITIONS AND METHODS FOR SUPPRESSING AND/OR TREATING HIV-INFECTION AND/OR A RELATED CLINICAL CONDITION THEREOF
Application Number: PCT/US2019/067936
Filing Date: December 20, 2019
Publication number: 20190010217
Abstract: Therapeutic compositions comprising one or more agents that inhibit the Nef-PAK2 interface, and methods of administering those therapeutic compositions to model, treat, reduce resistance to treatment, prevent, and diagnose a condition/disease associated with HIV-infection or a related clinical condition thereof, are disclosed.
Type: Application
Inventors: Matthias Alexander Clauss, Bernhard Fidelis Maier
